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  • Antacid medication in pregnancy may increase childhood asthma

    Children of mothers who took acid-suppressive drugs during pregnancy had a 1.5 times higher incidence of asthma when compared with children who were not exposed to the drugs in utero,…

  • Stem cell researcher honored by President George W. Bush

    Harvard Stem Cell Institute (HSCI) scientist Kevin Eggan today was cited by President George W. Bush for his work in advancing the field of stem cell science on both scientific…

  • Antacid use during pregnancy may increase childhood asthma

    Children of mothers who took acid-suppressive drugs during pregnancy had a 1.5 times higher incidence of asthma when compared with children who were not exposed to the drugs in utero, finds a large population-based study by researchers at Children’s Hospital Boston. The findings, accompanied by an editorial, appear online this week in “Early View” in the journal Clinical & Experimental Allergy. (They will be formally published online on Jan. 19 and will appear in the journal’s February print edition.)

  • New obesity-related genes identified

    A large international consortium has made significant inroads into uncovering the genetic basis of obesity, adding six new genetic variants to the two already linked to higher body mass index (BMI) in previous studies. Most of the newly discovered genes had never before been suspected of having a role in body weight and, curiously, many of the genes are active in the central nervous system, suggesting they may exert their effects via the brain. The study, from the Genetic Investigation of Anthropometric Traits (GIANT) consortium, appeared online in Nature Genetics on Dec. 14.

  • Pain is more intense when inflicted on purpose

    Researchers at Harvard University have discovered that our experience of pain depends in part on whether we think someone caused the pain intentionally. Participants in a study who believed they were getting an electrical shock from another person on purpose, rather than accidentally, rated the shock as more painful than those receiving the same shock thinking it was an accident. Participants seemed to get used to shocks that were delivered unintentionally, but those given on purpose had a fresh sting every time.

  • New label-free method tracks molecules and drugs in live cells

    A new type of highly sensitive microscopy developed by Harvard researchers could greatly expand the limits of modern biomedical imaging, allowing scientists to track the location of minuscule metabolites and…

  • Supply of board-certified emergency physicians unlikely to meet projected needs

    The number of physicians with board certification in emergency medicine is unlikely to meet the staffing needs of U.S. emergency departments in the foreseeable future, if ever.  In the December…

  • Researchers replicate ALS process in lab dish

    A Harvard Stem Cell Institute (HSCI) research team has succeeded in deriving spinal motor neurons from human embryonic stem cells, and has then used them to replicate the Amyotrophic Lateral Sclerosis (ALS) disease process in a laboratory dish.

  • Researchers successfully track voyage of single stem cell

    The title of the letter in the Dec. 3 edition of the journal Nature — “Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche” — doesn’t begin to describe it, this real-life, real-time view of a single stem cell making its way to its ultimate home inside the bone-marrow cavity of a living mouse.

  • Dybul urges partnering with governments, communities to fight AIDS

    In honor of World AIDS Day (Dec. 1), Ambassador Mark Dybul, the U.S. global AIDS coordinator who is leading the implementation of the $48 billion President’s Emergency Plan for AIDS Relief (PEPFAR), spoke Dec. 4 in Sever Hall.

  • Rights, AIDS, past and future

    Sixty years after the United Nations declared health care a basic human right, the AIDS epidemic highlights how much work remains to be done as the disease rages on among populations with little access to quality care.

  • Research may lead to treatment for retinitis pigmentosa

    Rods and cones coexist peacefully in healthy retinas. Both types of cells occupy the same layer of tissue and send signals when they detect light, which is the first step in vision.

  • Hormone therapy for prostate cancer does not appear to increase cardiac deaths

    Treating prostate cancer patients with drugs that block hormonal activity does not appear to increase the risk of death from cardiovascular disease, according to a study led by Harvard Medical…

  • Fresh insight into retinitis pigmentosa

    Rods and cones coexist peacefully in healthy retinas. Both types of cells occupy the same layer of tissue and send signals when they detect light, which is the first step…

  • Connie Cepko

    In some ways, Connie Cepko’s job has gotten easier. The Harvard Medical School genetics professor is working to uncover the mysteries of the eye, to understand how it develops and…

  • Another step forward in ALS and stem cell research

    A Harvard Stem Cell Institute research team has succeeded in deriving spinal motor neurons from human embryonic stem cells, and has then used them to replicate the Amyotrophic Lateral Sclerosis (ALS) disease process in a laboratory dish.

  • Some blood-system stem cells reproduce more slowly than expected

    A research collaboration lead by Harvard Stem Cell Institute researchers at Massachusetts General Hospital (MGH) has found a subpopulation of hematopoietic stem cells, which generate all blood and immune system…

  • Early success highlights need for more progress

    Many of the 500,000 African babies born infected with HIV each year won’t live past age 2, a fact made even more appalling by the fact that doctors know how to halt mother-to-child HIV transmission.

  • Cutler finds decline in cancer deaths

    Improvements in behavior and screening have contributed greatly to the 13 percent decline in cancer mortality since 1990, with better cancer treatments playing a supporting role, according to new research from David Cutler of Harvard University.

  • South African AIDS policy tied to 330,000 lives lost

    More than 330,000 lives were lost to HIV/AIDS in South Africa from 2000 and 2005 because a feasible and timely antiretroviral (ARV) treatment program was not implemented, assert researchers from…

  • Genetic screening no better than traditional risk factors for predicting type 2 diabetes

    Screening for a panel of gene variants associated with the risk for type 2 diabetes can identify adults at risk for the disorder but is not significantly better than assessment based on traditional risk factors such as weight, blood pressure, and blood sugar levels.

  • Anesthetic causes changes in mouse brains

    For the first time researchers have shown that a commonly used anesthetic can produce changes associated with Alzheimer’s disease in the brains of living mammals, confirming previous laboratory studies. In their Annals of Neurology report, which has received early online release, a team of Massachusetts General Hospital (MGH) investigators shows how administration of the gas isoflurane can lead to generation of the toxic amyloid-beta (A-beta) protein in the brains of mice.

  • For innovative undergrads, bacteria make some buzz

    A team of undergraduates who engineered a bacterial biosensor with electrical output recently made some buzz at the 2008 international Genetically Engineered Machine (iGEM) competition held at the Massachusetts Institute of Technology (MIT).

  • A single gene leads yeast cells to cooperate against threats

    An ingenious social behavior that mobilizes yeast cells to cooperate in protecting each other from stress, antibiotics, and other dangers is driven by the activity of a single gene, scientists report this week in the journal Cell. The cooperating cells use the same gene, dubbed FLO1, as a marker for detecting “cheaters,” cells that try to profit from the group’s protection without investing in the group’s welfare.

  • Drug trial shows dramatic reduction in hidden heart disease

    A Harvard-led study shows that the risk of heart attack and stroke among subjects with “silent heart disease” — and normal cholesterol levels — can be dramatically reduced by the use of an already widely prescribed class of drugs.

  • Common surgical anesthetic induces Alzheimer’s-associated changes in mouse brains

    For the first time researchers have shown that a commonly used anesthetic can produce changes associated with Alzheimer’s disease in the brains of living mammals, confirming previous laboratory studies.  In…

  • Drug trial shows dramatic reduction in risks posed by hidden heart disease

    A Harvard-led study shows that the risk of heart attack and stroke among subjects with “silent heart disease” — and normal cholesterol levels — can be dramatically reduced by the use of an already widely prescribed class of drugs.

  • C. Ronald Kahn first to win Manpei Suzuki International Prize for Diabetes Research

    C. Ronald Kahn, M.D., Mary K. Iacocca Professor of Medicine at Harvard Medical School, and head of the Head Section on Obesity and Hormone Action at the Joslin Diabetes Center,…

  • Microbiologist Gary Ruvkun:

    Gary Ruvkun has made a career out of imagining the unimaginable, and of surrounding himself with like-minded thinkers who let the wheels of thought spin until they catch on something…

  • Survey finds disconnect between sexual problems in women and feeling of distress

    The largest such study ever published finds that, although about 40 percent of women surveyed report having sexual problems, only 12 percent indicate that those issues are a source of…